Scientists of the International School for Advanced Studies (SISSA) of Triest have taken a first step toward the creation of functioning artificial cells by reproducing motility in their computer models, causing the “cells” to divide spontaneously without the action of external forces
APOLOGETIC but defiant. A young researcher who shot to fame for her simple way of turning adult cells into stem cells by bathing them in acid has been found guilty of misconduct, but claims the underlying science is sound.
The committee decided that two of these were deliberate alterations. One was a mislabelled image taken from her PhD thesis – something Obokata says was an accident. The other was an image of a control experiment done at a different time from the test it was compared with. Obokata says the image was enhanced but not falsified.
At a press conference last week, she apologised for the question marks over the work. She said they were due to her “carelessness, sloppiness and immaturity”, and that she “lacked proper knowledge regarding basic methods for writing theses on biological subjects and the way such papers should be presented”.
Obokata has filed a complaint against Riken, emphasising that there was no intent to deceive. She says that the mistakes don’t affect the conclusion of the paper and claims to have recreated these cells over 200 times. No external researcher has yet confirmed that they have done the same.
‘Together with other pollinators, bumblebees contribute more than £18billion (€22 billion euros) to European agriculture a year,’ its report said.
The biggest threat to bumblebees is the destruction of wildflower meadows which gives them a food supply.
The mass use of herbicides and pesticides has also been a big blow, with chemicals used to remove ‘weeds’ such as clover from farmlands that the insects feed on.
Half of Europe’s bumblebee species have falling populations and just 13 per cent are increasing, it said.
Using the model plant species Arabidopsis, the team demonstrated that a few pulses of bright light on a daily basis spurred the plants to begin making zeaxanthin in preparation for an expected excess of sunlight.
The pulses were short enough that they didn’t interfere with the otherwise optimal growing conditions, but long enough to cause accumulation of zeaxanthin.
Mitochondria generate a cell’s energy. It’s long been thought that an accumulation of free radicals, produced when cells metabolise, drives the ageing process by damaging DNA and proteins. Mitochondria are particularly at risk because they produce free radicals in large quantities but lack the DNA repair mechanisms found in other parts of the cell.
Dong’s team found that the number of “mitoflashes”, caused by the presence of free radicals, emitted when a nematode was three days old could predict its lifespan. Worms typically live for 21 days and are at their peak of reproductive fitness at 3 days old. Those with low mitoflash activity at that time lived longer, while those with high mitoflash activity died before day 21.
A new way to print living cells onto any surface and in almost any shape has been developed by researchers led by Houston Methodist Research Institute nanomedicine faculty member Lidong Qin.
Unlike a similar inkjet printing process, almost all cells survive.
Exotic animals can make popular pets but a cat with a touch of the supernatural will stand out in among the neighbours’ moggies.
A new breed of cat that looks like a werewolf and behaves like a dog has been developed by U.S. breeders
The Lykoi gets its spooky looks because of a genetic mutation in a domestic short hair cat, which prevents the curious creature from growing a full coat of fur, making it looks like a werewolf.
Bird-brained? This crow’s a genius! Amazing video reveals how creature solves 8 complex puzzles to unlock a treat
James Bond is known for his ability to make the best of a bad situation, but a crow called 007 has also proved to be a top notch problem solver.
The cunning crow has solved one of the most complex tests of the animal mind ever to be constructed.
And did so in less than three minutes on camera – a world first.
The beauty of genes: Scientists take stunning ‘photographs’ of human cells by making the DNA inside them GLOW
This hypnotic image is what the human body looks like when you break it down into its smallest parts.
It might seem like a piece of abstract art, but in reality these intricate patterns are the tiny scaffolds and components that make up a human cell.
Inside each cell is a huge range of molecular machinery that can resemble a busy construction site, with different types of these tiny cellular workers coming and going.
Last week, the scientific world was bowled over by a study in Nature showing that an acidic environment turned adult mouse cells into “totipotent” stem cells – which can turn into any cell in the body or placenta. The researchers called these new totipotent cells stimulus-triggered acquisition of pluripotency (STAP) cells.
“If they can do this in human cells, it changes everything,” Rob Lanza of Advanced Cell Technologies in Marlborough, Massachusetts, said at the time. The technique promises cheaper, quicker and potentially more flexible cells for regenerative medicine, cancer therapy and cloning.
Now, Vacanti and his colleagues say they have taken human fibroblast cells and tested several environmental stressors on them in an attempt to recreate human STAP cells. He won’t reveal what type of stressors were applied but he says the resulting cells appears similar in form to the mouse STAP cells. His team is in the process of testing to see just how stem-cell-like these cells are.
Vacanti says that the human cells took about a week to resemble STAP cells, and formed spherical clusters just like their mouse counterparts. Using a similar experimental set-up with green monkey (Chlorocebus sabaeus) cells, Vacanti says the resulting cells are behaving slightly differently. He says that may be due to the fact that the researchers used slightly different techniques. Both Vacanti and his Harvard colleague Koji Kojima emphasise that these results are only preliminary and much further analysis and validation is required.
“Even if these are STAP cells they may not necessarily have the same potential as mouse ones – they may not have the totipotency – which is one of the most interesting features of the mouse cells,” says Sally Cowley, head of the James Martin Stem Cell Facility at the University of Oxford.
Pluripotent cells, such as embryonic stem cells, can form any cell in an embryo but not a placenta. Totipotent cells, however, can form any cell in an embryo and a placenta – meaning they have the potential to create life. The only cells known to be naturally totipotent are in embryos that have only undergone the first couple of cell divisions immediately after fertilisation.
University of Illinois researchers have developed a new imaging technique that needs no dyes or other chemicals, yet renders high-resolution, three-dimensional, quantitative imagery of cells and their internal structures using conventional microscopes and white light.
Called white-light diffraction tomography (WDT), the imaging technique opens a window into the life of a cell without disturbing it and could allow cellular biologists unprecedented insight into cellular processes, drug effects and stem cell differentiation.
“One main focus of imaging cells is trying to understand how they function, or how they respond to treatments, for example, during cancer therapies,” Popescu said. “If you need to add dyes or contrast agents to study them, this preparation affects the cells’ function itself. It interferes with your study. With our technique, we can see processes as they happen and we don’t obstruct their normal behavior.”
What does a dolphin use to get high? A toxic puffer fish that makes them lapse into a trance-like state
Zoologist and series producer Rob Pilley said that it was the first time dolphins had been filmed behaving this way.
He added: ‘We saw the dolphins handle the puffers with kid gloves, very gently and delicately like they were almost milking them to not upset the fish too much or kill it.
‘As a result the fish released various toxins as a defence.
‘The dolphins then seemed to be mesmerised.’
He insisted that the scene couldn’t have been a one-off encounter, saying: ‘The dolphins were specifically going for the puffers and deliberately handling them with care.’
Other than the American alligator, the savannah monitor lizard is the only other known reptile found the ability to breathe in this way – also known as unidirectional breathing.
This is in contrast to humans and other mammals who have a two-way, or ‘tidal’, breathing pattern.
Tidal breathing means air enters the lungs through airways and then flows back out again the same way.
Rather than being partially filled with stale air like human lungs, a bird’s lungs contain air with much higher oxygen content to help them fly.
But we can speculate on what the possible explanation might be. It could mean there is a sub species of brown bear in the High Himalayas descended from the bear that was the ancestor of the polar bear. Or it could mean there has been more recent hybridisation between the brown bear and the descendent of the ancient polar bear.
What a way to go! Male marsupial found to sex itself to death after intensive 14-hour mating sessions in its final fortnight
The mouse-like creature, which only lives for a year, has sex so often in the last two weeks of its life that is loses all its fur, becomes infected, bleeds internally and eventually dies.
Lead researcher Dr Diana Fisher said: ‘Poor little guys – you have to feel sorry for them.
But in a first-of-its-kind study published today in the journal PLOS ONE, scientists at the University of Maryland and the US Department of Agriculture have indentified a witch’s brew of pesticides and fungicides contaminating pollen that bees collect to feed their hives. The findings break new ground on why large numbers of bees are dying though they do not identify the specific cause of CCD, where an entire beehive dies at once.When researchers collected pollen from hives on the east coast pollinating cranberry, watermelon and other crops and fed it to healthy bees, those bees showed a significant decline in their ability to resist infection by a parasite called Nosema ceranae.
Scientists develop tough petunia plant which survives temperatures of -10C and will continue flowering through winter
The petunia ‘Below Zero’ plants come in batches of five plugs and cost £7.
Back from the dead, nearly: Scientists create living embryo of extinct frog that gives birth through its MOUTH
Jesus wept: Like Lazarus, the long-extinct gastric-brooding frog, Rheobatrachus silus, could be be brought back to life – some 30 years after the last living specimen died out
Scientists ’embalm’ the living cell in a silica acid solution
Fossilised cell can survive greater temperatures and pressures than flesh
Researchers from Sandia National Laboratories and University of New Mexico hope technique can used in commercial manufacturing
The Sauron dinosaur: Palaeontologists name beast after Tolkien’s demonic creation after it is identified from just its eye-socket
Sauroniops pachytholus was one of four large predatory dinosaurs which lived in North Africa 95million years ago
Scientists estimate that it was as much as 40ft long and similar in shape but unrelated to Tyrannosaurus rex
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