Nanoparticles may offer cure for MS
The new nanotechnology can also, they say, be applied to a variety of immune-mediated diseases including Type 1 diabetes, along with food and airway allergies.
And it doesn’t suppress the entire immune system, as do current therapies, which make patients more susceptible to everyday infections and cancer. Rather, when the nanoparticles are attached to myelin antigens and injected into the mice, the immune system is reset to normal.
“This is a highly significant breakthrough in translational immunotherapy,” says Stephen Miller of the Northwestern University Feinberg School of Medicine. “The beauty of this new technology is it can be used in many immune-related diseases. We simply change the antigen that’s delivered.”
The nanoparticle is made from an easily-produced and already FDA-approved substance – a polymer called Poly(lactide-co-glycolide) (PLG), which consists of lactic acid and glycolic acid, both natural metabolites in the human body. It’s most commonly used for biodegradable sutures.
“We administered these particles to animals who have a disease very similar to relapsing remitting multiple sclerosis and stopped it in its tracks,” says Miller. “We prevented any future relapses for up to 100 days, which is the equivalent of several years in the life of an MS patient.”
Shea and Miller are now testing the nanoparticles to treat Type one diabetes and airway diseases such as asthma.
No comments yet.
- Major drug company to market implantable microchips that deliver drugs inside the body
- Play the online game that claims to help you shed 0.7kg in ONE WEEK
- Brain scans reveal anxious parents are more likely to have nervous and depressed children
- Study finds dramatic differences in the way we age
- Elon Musk spends $10 million on new projects to control AI
- GoPro reveals new $400 mini camera it claims can record HD video anywhere – and even capture audio underwater
- CityLab shows how electric cars can be WORSE for the environment than gas-guzzling vehicles
- Tetris blocks traumatic flashbacks even after the memory is fixed
- Modified mosquitoes begin blitz on dengue in Brazilian city
- LG’s New Displays Will Make Laptops Slimmer And Lighter
- Samsung cranks SSDs to 2TB with the 850 Pro and EVO
- Blogs RO
- Famous Quotes
- Food recipises
- Health – Brain
- IT Hardware