Nanoparticles may offer cure for MS
The new nanotechnology can also, they say, be applied to a variety of immune-mediated diseases including Type 1 diabetes, along with food and airway allergies.
And it doesn’t suppress the entire immune system, as do current therapies, which make patients more susceptible to everyday infections and cancer. Rather, when the nanoparticles are attached to myelin antigens and injected into the mice, the immune system is reset to normal.
“This is a highly significant breakthrough in translational immunotherapy,” says Stephen Miller of the Northwestern University Feinberg School of Medicine. “The beauty of this new technology is it can be used in many immune-related diseases. We simply change the antigen that’s delivered.”
The nanoparticle is made from an easily-produced and already FDA-approved substance – a polymer called Poly(lactide-co-glycolide) (PLG), which consists of lactic acid and glycolic acid, both natural metabolites in the human body. It’s most commonly used for biodegradable sutures.
“We administered these particles to animals who have a disease very similar to relapsing remitting multiple sclerosis and stopped it in its tracks,” says Miller. “We prevented any future relapses for up to 100 days, which is the equivalent of several years in the life of an MS patient.”
Shea and Miller are now testing the nanoparticles to treat Type one diabetes and airway diseases such as asthma.
No comments yet.
- What causes autism? Scientists discover people with the condition have too many brain ‘connections’
- Google’s fact-checking bots build vast knowledge bank
- Young blood to be used in ultimate rejuvenation trial
- Official Destiny – Launch Gameplay Trailer
- Could LIZARDS be the key to regrowing human limbs?
- Samsung PN51F8500 51-Inch Plasma TV Verdict
- Netgear R8000 Nighthawk X6 AC 3200 Tri-Band WiFi Router Review
- Adaptive Material Inspired By Octopus Skin
- Neuromorphic ‘atomic-switch’ networks function like synapses in the brain
- Earth is in overdraft just EIGHT months into the year: We’ve now exhausted our natural budget for land, trees and food, warn campaigners
- Scientists bypass spinal column non-invasively to trigger walking
- Sharp’s one-bezel Aquos Crystal smartphone is headed to the US
- Blogs RO
- Famous Quotes
- Food recipises
- IT Hardware