Grape seed extract kills head and neck cancer cells, leaves healthy cells unharmed

Grape seed extract creates these conditions that are unfavorable to growth. Specifically, the paper shows that grape seed extract both damages cancer cells’ DNA (via increased reactive oxygen species) and stops the pathways that allow repair (as seen by decreased levels of the DNA repair molecules Brca1 and Rad51 and DNA repair foci).

“Yet we saw absolutely no toxicity to the mice, themselves,” Agarwal says.

Again, the grape seed extract killed the cancer cells but not the healthy cells.

“I think the whole point is that cancer cells have a lot of defective pathways and they are very vulnerable if you target those pathways. The same is not true of healthy cells,” Agarwal says.

Grape seed extract kills head and neck cancer cells, leaves healthy cells unharmed

New Virtual Helper Challenges Siri

True Knowledge is hoping the semantic database it has built up over the past few years could provide this edge.

Evi’s availability and promise as an artificial intelligence app, coupled with its low price (99 cents on the iPhone and free on Android phones), caused its popularity to skyrocket following its Monday release, and made it difficult for those downloading it to try it out. Evi isn’t the only Siri competitor—and in fact its capabilities are somewhat different from Siri’s offerings—but plenty of smart-phone users, it seems, are eager for Evi’s help in particular.
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Essentially, the app takes your spoken or typed question and uses its vast store of knowledge along with outside data from websites like Yelp to give pertinent answers. This is similar to how Siri works, but Apple’s assistant focuses more on accomplishing tasks, such as making calls, setting alerts, or dictating text messages, by working with the iPhone’s other apps. Evi does not do these things, but Tunstall-Pedoe says it will eventually be able to take on more tasks.

New Virtual Helper Challenges Siri – Technology Review